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Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
Sponsor: EXACT Therapeutics AS
Summary
The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.
Official title: A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2025-06-19
Completion Date
2027-07-15
Last Updated
2026-04-03
Healthy Volunteers
No
Interventions
Acoustic Cluster Therapy
Drug: PS101; Device: Ultrasound
Modified FOLFIRINOX
Chemotherapy
Locations (10)
HonorHealth Research Institute
Scottsdale, Arizona, United States
Stanford Cancer Center Palo Alto
Stanford, California, United States
Beth Israel Deaconess Medical Center - Division of Hematology/Oncology
Boston, Massachusetts, United States
Henry Ford Centre
Detroit, Michigan, United States
Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Brown University Cancer Institute
Providence, Rhode Island, United States
CAMBRIDGE CANCER TRIALS CENTRE-Addenbrooke's Hospital
Cambridge, Cambridge, United Kingdom
Gary Weston Centre- Imperial College Healthcare- Du Cane Road
Hammersmith, London, United Kingdom
The Royal Marsden- Downs Road
Sutton, Surrey, United Kingdom