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Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns
Sponsor: The First Hospital of Jilin University
Summary
This prospective cohort study aims to investigate the impact of early antibiotic exposure on the establishment of gut microbiota and motility in newborns, particularly preterm infants. The study will explore the correlation between antibiotic exposure, gut microbiota colonization, and 5-hydroxytryptamine (5-HT) levels, which are critical for gastrointestinal motility. The findings may provide insights into optimizing antibiotic use and improving gastrointestinal health in neonates.
Official title: Effects of Early Antibiotic Exposure on Gut Microbiota and Motility Establishment in Newborns: a Prospective Cohort Study
Key Details
Gender
All
Age Range
24 Weeks - 36 Weeks
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2025-02-01
Completion Date
2027-05-30
Last Updated
2025-02-28
Healthy Volunteers
No
Conditions
Locations (1)
The first hospital of Jilin university
Changchun, Jilin, China