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TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use
Sponsor: University of Colorado, Denver
Summary
The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia. The main question it aims to answer is: • Can a mhealth peer navigator intervention effectively promote HIV pre-exposure prophylaxis PrEP use among high-risk female students in Zambia? Researchers will compare the mhealth peer navigator intervention to treatment as usual to see if there are effects on female student's use and continuation of PrEP for HIV prevention. Participants in the intervention will be paired with a trained peer navigator who will offer education, social support, and help navigating the health systems to access PrEP and other sexual and reproductive health services. All participants in both arms will complete surveys at baseline, 6 months, and 12 months to evaluate health behaviors.
Official title: TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use Among Sexually Active Female University Students in Zambia: Study Protocol of a Hybrid Effectiveness-implementation Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
18 Years - 24 Years
Study Type
INTERVENTIONAL
Enrollment
324
Start Date
2025-02-18
Completion Date
2026-08-31
Last Updated
2025-02-28
Healthy Volunteers
Yes
Conditions
Interventions
TwySHE
Interpersonal support from trained peers to access and use PrEP and contraception.
Locations (1)
University of Zambia
Lusaka, Zambia