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ENROLLING BY INVITATION
NCT06853327
PHASE2

Oral Ketorolac for IUD Pain Reduction

Sponsor: University of North Carolina, Chapel Hill

View on ClinicalTrials.gov

Summary

To determine if oral ketorolac given at different timepoints prior to intrauterine device (IUD) insertion influences pain experienced during this procedure.

Official title: Timing of Oral Ketorolac for Pain Reduction in IUD Insertion: A Double-Blind Randomized Controlled Trial

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

108

Start Date

2025-05-23

Completion Date

2026-06-30

Last Updated

2025-05-30

Healthy Volunteers

Yes

Interventions

DRUG

Ketorolac

The experimental condition to be examined by this study is the timing of administration of ketorolac prior to IUD insertion. Ketorolac 20mg PO has proven beneficial at certain timepoints during IUD insertion in prior studies, but pharmacokinetics indicate that it could require more time until peak analgesia.

DRUG

Placebo

Placebo will be used to control the timing of administration and be used to compare ketorolac to baseline standard pain control regimens

Locations (1)

University of North Carolina - Hillsborough Campus

Hillsborough, North Carolina, United States