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A Study on the Changes and Prognosis of Intestinal Microbiota and Function in Infants With Food Allergies
Sponsor: Ruijin Hospital
Summary
Microorganisms maintain a complex interrelationship with the human body, influencing each other. In recent years, people have gradually realized that the formation of the pediatric microecosystem is closely related to the development of gastrointestinal and even systemic immunity in children. The establishment of the pediatric microecosystem during childhood has significant implications for various diseases in adulthood. They are crucial for the host's nutrition, metabolism, resistance to pathogens, and immune function. Increasing evidence supports the association between gut microbiota abnormalities and the pathophysiology of food allergies, but the conclusions of existing clinical efficacy studies remain controversial. Previous research by the team has found that the gut microbiome has a clear impact on the occurrence and development of digestive and allergic diseases in children.
Key Details
Gender
All
Age Range
1 Month - 36 Months
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-02-01
Completion Date
2028-02-01
Last Updated
2025-03-03
Healthy Volunteers
Yes
Conditions
Locations (1)
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China