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ENROLLING BY INVITATION
NCT06855355
NA

CBM588 Reduces Colorectal Polyp Recurrence

Sponsor: Kaohsiung Medical University

View on ClinicalTrials.gov

Summary

The goal of this randomized crossover clinical trial is to evaluate the efficacy of Clostridium butyricum MIYAIRI 588 (CBM588) in reducing colorectal adenomatous polyp recurrence in adult patients with a history of colorectal polyps. The main questions it aims to answer are: * Does CBM588 reduce the recurrence of colorectal adenomatous polyps? * Does CBM588 lead to a sustained decrease in polyp burden over time? Researchers will compare a group receiving CBM588 in the first year to a group receiving CBM588 in the second year (after a washout period) to determine whether CBM588 effectively lowers polyp recurrence rates and adenoma prevalence.

Official title: Clostridium Butyricum MIYAIRI 588 Reduces Colorectal Adenomatous Polyp Recurrence: A Randomized Crossover Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

500

Start Date

2017-03-10

Completion Date

2028-12-31

Last Updated

2025-05-16

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Clostridium butyricum MIYAIRI 588

A butyrate-producing probiotic, has demonstrated potential anti-inflammatory and anti-tumorigenic effects.

Locations (1)

Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan, Taiwan