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NCT06855992
NA

Transcutaneous Laser Therapy in Chronic Kidney Disease

Sponsor: National Cheng-Kung University Hospital

View on ClinicalTrials.gov

Summary

Chronic kidney disease (CKD) affects approximately 10% of the global population, totaling over 800 million people. In Taiwan, one in eight individuals is diagnosed with CKD. According to National Health Insurance data, acute kidney injury and CKD rank first in medical expenditures, imposing a significant burden on patients' quality of life and the national healthcare system. Early intervention in CKD, especially for high-risk populations (e.g., individuals with diabetes or early-stage kidney dysfunction), can slow disease progression, delay the onset of kidney failure, and postpone the need for dialysis. Transcutaneous venous laser therapy is a non-invasive treatment. Current literature has demonstrated that it enhances blood circulation, alters blood and erythrocyte activity, and exhibits immunomodulatory, anti-inflammatory, and vasodilatory effects on the blood. Additionally, it boosts mitochondrial activity, which is crucial as mitochondria act as the energy powerhouses of cells, providing the necessary energy for kidneys to maintain normal function. This project aims to investigate whether this non-invasive transcutaneous venous laser therapy can reduce inflammation, improve physical activity, and further enhance patients' quality of life. It also seeks to reduce patients' medical expenses and National Health Insurance costs.

Official title: The Effects of Transcutaneous Laser Therapy in Chronic Kidney Disease

Key Details

Gender

All

Age Range

20 Years - Any

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-03-17

Completion Date

2026-01-31

Last Updated

2025-03-18

Healthy Volunteers

No

Interventions

DEVICE

Laser

60-minute 635 nm red laser intervention 3 times per week for 8 weeks

DEVICE

Red Light

60-minute red light sham intervention three times per week for 8 weeks