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RAFT-TAVR PACE: LBBAP Vs. RVP Post-TAVR in Patients Requiring PPI
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Summary
The RAFT-TAVR PACE study is a clinical trial designed to compare two types of heart pacing methods in patients who develop conduction problems after undergoing a transcatheter aortic valve replacement (TAVR) procedure. This study will evaluate whether Left Bundle Branch Area Pacing (LBBAP), a newer and more natural pacing method, is better than the traditional Right Ventricular Pacing (RVP) at improving heart function and patient outcomes. The study aims to recruit 60 patients across six centers and will focus on the safety, feasibility, and success of LBBAP compared to RVP. Patients will be followed for one year to assess heart function, quality of life, and any complications related to the pacing method.
Official title: Randomized Assessment of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Post-TAVR Patients with Persistent High-Degree Atrioventricular Block or Complete Heart Block Requiring Permanent Pacemaker Implantation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
430
Start Date
2025-04-01
Completion Date
2028-12-31
Last Updated
2025-03-04
Healthy Volunteers
No
Conditions
Interventions
Left Bundle Branch Area Pacing
LBBAP is performed during permanent pacemaker implantation post-TAVR.
Right Ventricular Pacing
RVP is performed during permanent pacemaker implantation post-TAVR.