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NOT YET RECRUITING
NCT06857201
NA

RAFT-TAVR PACE: LBBAP Vs. RVP Post-TAVR in Patients Requiring PPI

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

View on ClinicalTrials.gov

Summary

The RAFT-TAVR PACE study is a clinical trial designed to compare two types of heart pacing methods in patients who develop conduction problems after undergoing a transcatheter aortic valve replacement (TAVR) procedure. This study will evaluate whether Left Bundle Branch Area Pacing (LBBAP), a newer and more natural pacing method, is better than the traditional Right Ventricular Pacing (RVP) at improving heart function and patient outcomes. The study aims to recruit 60 patients across six centers and will focus on the safety, feasibility, and success of LBBAP compared to RVP. Patients will be followed for one year to assess heart function, quality of life, and any complications related to the pacing method.

Official title: Randomized Assessment of Left Bundle Branch Area Pacing Versus Right Ventricular Pacing in Post-TAVR Patients with Persistent High-Degree Atrioventricular Block or Complete Heart Block Requiring Permanent Pacemaker Implantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

430

Start Date

2025-04-01

Completion Date

2028-12-31

Last Updated

2025-03-04

Healthy Volunteers

No

Interventions

PROCEDURE

Left Bundle Branch Area Pacing

LBBAP is performed during permanent pacemaker implantation post-TAVR.

PROCEDURE

Right Ventricular Pacing

RVP is performed during permanent pacemaker implantation post-TAVR.