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Optimizing Deep Brain Stimulation to Improve Visuomotor Function in Parkinson's Disease
Sponsor: VA Office of Research and Development
Summary
Inability to align and refocus the eyes on the objects at different depths, i.e., vergence impairment and strabismus, frequently affects the quality of life in patients with Parkinson's disease. The investigators study aims to understand the location-specific effects of subthalamic region deep brain stimulation on vergence and strabismus by integrating the patient-specific deep brain stimulation models and high-resolution eye-tracking measures. The knowledge gained will allow the investigators to find the most beneficial stimulation location and parameters for improving binocular coordination, strabismus, and vergence while preserving the ability to treat motor symptoms in Parkinson's disease.
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2026-02-01
Completion Date
2029-10-01
Last Updated
2026-01-07
Healthy Volunteers
No
Conditions
Locations (1)
Louis Stokes VA Medical Center, Cleveland, OH
Cleveland, Ohio, United States