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Intra-Abdominal Instillation Of Fresh Frozen Plasma Versus Corticosteroids In Prevention Of Recurrent Attacks Of Adhesive Intestinal Obstruction: A 2 Years' Experience Clinical Study
Sponsor: Zagazig University
Summary
Adhesive Intestinal obstruction is an inevitable complication of abdominal surgery with significant morbidity associated with poor quality of life and predispose to repeated hospitalization. Most of them (73% - 90%) can be managed conservatively.Despite advances in surgery, 15to 30% require surgical intervention primarily or due to failure of conservative management. Because of the nature of the disease recurrence has been estimated to be 30%.Many attempts to prevent formation of postoperative adhesions have been tried. In this trial, we will study the effect of corticosteroids and FFP in prevention of adhesive small bowel obstruction recurrence for follow up of 2 years duration.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
176
Start Date
2025-03-01
Completion Date
2027-03-01
Last Updated
2025-08-14
Healthy Volunteers
No
Conditions
Interventions
intra-abdominal instillation of corticosteroids
after adhesiolysis, peritoneal lavage with diluted corticosteroids will be instillated intra-abdominally
intra-abdominal instillation of fresh frozen plasma
after adhesiolysis, peritoneal lavage with diluted FFP will be instillated intra-abdominally
Locations (2)
Faculty of Medicine
Zagazig, Sharqia Province, Egypt
Zagazig University Hospitals
Zagazig, zagazig, Egypt