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Melatonin for Patients With Chronic Low Back Pain
Sponsor: Bart Koes
Summary
Low back pain is one of the conditions causing more disability worldwide. The use of pain medications is substantial in patients with chronic LBP. But the efficacy of commonly used analgesics is modest. More than half of patients with chronic LBP also has sleep problems. In recent years, some preliminary studies have shown a promising effect of melatonin for the treatment of pain. The objective of this study is to investigate the efficacy of melatonin, relative to placebo, in patients with chronic LBP.
Official title: Melatonin for Patients With Chronic Low Back Pain - a Randomized Placebo-controlled Trial
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
240
Start Date
2025-04-11
Completion Date
2026-12
Last Updated
2025-08-22
Healthy Volunteers
No
Conditions
Interventions
Melatonin 10 mg
10 mg melatonin daily for a period of 6 weeks
Placebo
Daily placebo for a period of 6 weeks
Locations (1)
Erasmus MC
Rotterdam, Netherlands