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Heterogeneity of Oral Squamous Cell Carcinoma Analysis by Single Cell RNA Sequencing
Sponsor: Centre Leon Berard
Summary
The goal of this project is to characterise the heterogeneity of all cell populations (tumour cells, stromal and immune microenvironment) present in the tumor and their normal (and leucoplasic) counterparts by scRNAseq in OSCC patients.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-05-15
Completion Date
2028-05-15
Last Updated
2025-03-06
Healthy Volunteers
No
Conditions
Interventions
Biospecimen
* 1 or 2 tumoral specimen (depending on the size of the tumor) * 1 specimen of the healthy oral mucosa * 1 leucoplakia specimen if applicable. The biospecimens will be collected at the time of the surgery organised for the standard routine medical care.
Blood sampling
Blood sampling (6 mL), taken from a routine biological exam.
Locations (1)
Centre Léon Bérard
Lyon, France