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RECRUITING
NCT06861868
NA

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Sponsor: Johns Hopkins University

View on ClinicalTrials.gov

Summary

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.

Official title: Early Brain Development and Child Nutrition and Obesity

Key Details

Gender

All

Age Range

7 Years - 12 Years

Study Type

INTERVENTIONAL

Enrollment

210

Start Date

2024-12-02

Completion Date

2029-03-31

Last Updated

2026-05-07

Healthy Volunteers

Yes

Interventions

OTHER

fMRI cue reactivity task

Measures effect of food and non-food cues on brain activation

OTHER

fMRI go no go task

Measures effect of food and non-food cues on inhibitory responses and brain activation

OTHER

Ad libitum meal test

Measures effect of exposure to multi-item buffet meal on food intake

OTHER

Eating in the absence of hunger test

Measures effect of exposure to palatable snacks on food intake

Locations (4)

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Baltimore, Maryland, United States

Johns Hopkins University School of Medicine

Baltimore, Maryland, United States

Rhode Island Hospital

Providence, Rhode Island, United States

University of Washington

Seattle, Washington, United States