Clinical Research Directory
Browse clinical research sites, groups, and studies.
Intravesical Ozone Therapy for Interstitial Cystitis/Bladder Pain Syndrome
Sponsor: Medipol University
Summary
This randomized, double-blind, placebo-controlled trial evaluated the efficacy and safety of intravesical ozone therapy in 60 patients with interstitial cystitis (IC). Participants were assigned to ozone therapy, placebo, or standard care groups for 3 weeks, with follow-up at 6 weeks. The primary outcome was the change in O'Leary-Sant ICSI score. Secondary outcomes included VAS pain score, SF-36 physical health, and urinary frequency.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-06-01
Completion Date
2026-06-01
Last Updated
2025-04-27
Healthy Volunteers
No
Interventions
Intravesical Ozone Therapy
Patients received 50 mL ozonated saline (20-40 µg/mL) intravesically twice weekly for 3 weeks.
Placebo (Normal Saline)
Patients received 50 mL normal saline intravesically twice weekly for 3 weeks.
Control
Patients continued standard care (e.g., oral pentosan polysulfate) without intravesical intervention.
Locations (1)
İstanbul Başakşehir Çam Ve Sakura Şehir Hastanesi
Istanbul, Turkey (Türkiye)