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Dual-energy SPEctral CT to Evaluate Response to First-line Therapies in Patients With Metastatic Clear Cell REnal Cancer
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
To evaluate the utility of dual-energy spectral computed tomography (CT) scan in monitoring treatment in patients with metastatic clear cell carcinoma of the kidney. In particular, to analyze the use of spectral CT in patients who are candidates to receive first-line treatment based on combinations of immunotherapy and molecularly targeted drugs. In particular, the parameters derived from the use of this technology and their variation during therapy will be analyzed together with some possible molecular alterations highlighted by the analysis of the tumor tissue previously taken from the patient, relating them to the response to first-line therapy with immuno-combinations.
Official title: Dual-energy SPEctral CT to Evaluate Response to New First-line Therapies in Patients With Metastatic Clear Cell REnal Cancer and the Association of Its Parameters With Molecular Alterations
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
50
Start Date
2024-09-30
Completion Date
2027-08-31
Last Updated
2025-03-07
Healthy Volunteers
No
Conditions
Locations (2)
Irccs Azienda Ospedaliero Universitario Di Bologna
Bologna, BO, Italy
Oncology Unit, IRCCS Azienda Ospedaliero Universitaria Bologna
Bologna, Italy