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Quality of Life and Long-term Outcome of Adequately Treated Congenital Hypothyroidism
Sponsor: Federico II University
Summary
The primary objective of this observational study is the evaluation of the quality of life and long-term outccome of young-adult patients with congenital hypothyroidism diagnosed by neonatal screening receiving replacement treatment with levothyroxine. The secondary objective is to relate the results to the form of hypothyroidism, the initial dose of L-T4, treatment adherence and genetics
Official title: Quality of Life and Long-term Outcome of Transition-age Patients With Congenital Hypothyroidism Diagnosed by Newborn Screening and Adequately Treated
Key Details
Gender
All
Age Range
16 Years - 21 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2024-09-06
Completion Date
2025-12-31
Last Updated
2025-03-07
Healthy Volunteers
No
Conditions
Interventions
SF36 test
Assessment of quality of life by administering the SF36 test
WAIS IV test
Assessment of cognitive abilities by administering the WAIS IV test
SCL-90 psychopathological screening questionnaire
Assessment of any psychopathological conditions by means of the SCL-90 psychopathological screening questionnaire
CBCL questionnaire
For patients up to 18 years of age: CBCL questionnaire to be administered to parents to describe the patient's behavior
bioimpedance analysis
Assessment of body composition by performing bioimpedance analysis
Locations (1)
Pediatric Endocrinology Program, Department of the Mother and the Child, University Federico II of Naples
Naples, Italy