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The Incidence of New-brain Lesions on Brain MRI and Safety Between Edoxaban and Apixaban in Patients with Stroke and Nonvalvular Atrial Fibrillation
Sponsor: Ewha Womans University Seoul Hospital
Summary
This study aims to determine whether there is a difference in brain lesion occurrence and safety when brain MRI is followed up between edoxaban and apixaban in stroke patients with nonvalvular atrial fibrillation through exploratory clinical trials.
Official title: A Randomized, Open-label, Investigator-led, Pilot Trial Investigating the Incidence of New-brain Lesions on Brain MRI and Safety Between Edoxaban and Apixaban in Patients with Stroke and Nonvalvular Atrial Fibrillation
Key Details
Gender
All
Age Range
19 Years - Any
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2025-03-01
Completion Date
2029-12-31
Last Updated
2025-03-07
Healthy Volunteers
No
Conditions
Interventions
Administration of Apixaban
Apixaban 2.5mg BID or Apixaban 5mg BID
Administration of Edoxaban
Edoxaban 15mg QD or Edoxaban 30mg QD or Edoxaban 60mg QD
Locations (1)
Ewha Womans University Medical Center
Seoul, Seoul, South Korea