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Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder
Sponsor: Centre Hospitalier Universitaire de Besancon
Summary
The goal of this exploratory, interventional, multicentre study is to compare the prefrontal activity during a negative emotion regulation task in women with Binge-Eating Disorder (BED) and healthy women with and without Emotional Eating (EE). The aim of this study is to compare the prefrontal processing of cognitive control of emotions between BED and EE and to compare the emotional processing and emotional experience between BED and EE. The study will thus compare four experimental groups: patients with BED, BMI-matched healthy volunteers with EE, BMI-matched healthy volunteers, and healthy volunteers of normal weight without BED. Participants will perform a down-regulation task of negative emotions elicited by negative pictures. During this task, their cerebral activity will be recorded using functional near-infrared spectroscopy (fNIRS), as well as their autonomous activity (skin conductance, pulse rate, respiration rate).
Key Details
Gender
FEMALE
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-06-24
Completion Date
2026-10-30
Last Updated
2025-07-22
Healthy Volunteers
Yes
Interventions
Emotion regulation task (fNIRS recording during the emotional regulation task)
No drugs were used in this study. All participants perform an emotion regulation task. More precisely, they have to down regulate negative emotions elicited by negative pictures using a cognitive reaprasal strategy. To this end, they have to change the meaning of the picture they are watching in order to decrease motional intensity.
Locations (3)
UFC - UFR Santé
Besançon, France
CHU de Besançon
Besançon, France
CHU de Dijon
Dijon, France