Clinical Research Directory

Inclusion Criteria: * Hospitalized at Primary Children's Hospital on units 3 Southeast, 3 Northeast, 3 Northwest * Age 1-18 years * Pediatric Early Warning Score ≤ 1 at 2000 * A parent/home caregiver present to consent to study * Patient and home caregiver speak English or Spanish. * Deemed appropriate for forgone overnight vital signs by care team (attending MD/Advanced Practice Provider and bedside RN). Exclusion Criteria: * Pre-existing diagnosis of hypertension, kidney disease, pulmonary hypertension, chronic lung disease, congenital heart disease causing cardiopulmonary compromise, obstructive sleep apnea, seizure disorder, neuromuscular disability. * Patients requiring O2 monitoring at home. * The following medications in the previous 24 hours: opioids, intravenous immunoglobulin, intravenous magnesium, continuous albuterol, benzodiazepines, other sedating medications beyond home regimen. * Anaphylaxis within 24 hours * Within the first 24 hours post-operative period * Requiring oxygen above baseline * Fever in the last 24 hours. * Sepsis alert in the last 72 hours.