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RECRUITING
NCT06867926
NA

The Effect of Cardiac Rehabilitation on Oxidative DNA Damage and Inflammation in Patients With Coronary Artery Disease

Sponsor: TC Erciyes University

View on ClinicalTrials.gov

Summary

The objective of this study was to determine the levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), an indicator of oxidative stress, and to demonstrate oxidative DNA damage in cardiac rehabilitation treatment in patients with coronary artery disease. Additionally, proinflammatory cytokines TNFα, IL-1β, and IL-6 levels were measured to evaluate the significance of cardiac rehabilitation treatment in patients with coronary artery disease and to assess the correlation between cytokine levels and 8-OHdG levels.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

70

Start Date

2025-05-15

Completion Date

2025-12-01

Last Updated

2025-05-02

Healthy Volunteers

Yes

Interventions

OTHER

Cardiac rehabilitation

Individuals diagnosed with coronary artery disease will engage in a programme of cardiac rehabilitation.

Locations (1)

Erciyes University Faculty of Medicine

Kayseri, Turkey (Türkiye)