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The Effect of Cardiac Rehabilitation on Oxidative DNA Damage and Inflammation in Patients With Coronary Artery Disease
Sponsor: TC Erciyes University
Summary
The objective of this study was to determine the levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), an indicator of oxidative stress, and to demonstrate oxidative DNA damage in cardiac rehabilitation treatment in patients with coronary artery disease. Additionally, proinflammatory cytokines TNFα, IL-1β, and IL-6 levels were measured to evaluate the significance of cardiac rehabilitation treatment in patients with coronary artery disease and to assess the correlation between cytokine levels and 8-OHdG levels.
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2025-05-15
Completion Date
2025-12-01
Last Updated
2025-05-02
Healthy Volunteers
Yes
Conditions
Interventions
Cardiac rehabilitation
Individuals diagnosed with coronary artery disease will engage in a programme of cardiac rehabilitation.
Locations (1)
Erciyes University Faculty of Medicine
Kayseri, Turkey (Türkiye)