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Predict CHimio-or Radiation-induced NAusea and Vomiting in Children/adolescents Treated for Cancer
Sponsor: Rennes University Hospital
Summary
Chemo- or radiation-induced nausea and vomiting (CRVN) is one of the most frequent and feared side effects. It is a symptom that is few or not at all evaluated. There is a significant discrepancy between the perception of the CRVN symptom by caregivers and the patient's own experience. At present, there is no real consensus to manage CRVN with medication, and CRVN relief is also the subject of heterogeneous practices. The importance of primary prevention of CRVN, before starting the first treatment sequence, has been highlighted to optimize the action of antiemetic treatments and limit the risk of anticipated nausea and vomiting (NV). The investigators' objective is to objectively assess the risk of CRVN in children/adolescents treated for cancer (and thus effectively prevent this symptom).
Official title: Prévoir Les NAusées Et Vomissements CHimio Ou Radio-induits Chez Les Enfants/adolescents Traités Pour Un Cancer
Key Details
Gender
All
Age Range
4 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2025-03
Completion Date
2026-07
Last Updated
2025-03-11
Healthy Volunteers
No
Interventions
BARF scale
BARF Scale, validated in paediatrics, is graduated from 0 to 10 and shows 6 increasingly nauseous faces. A child/adolescent will be considered "at risk of NV" if he/she declares a score greater than or equal to 4 out of 10 on at least one of the 4 observation times. This scale can be used by the child him/herself, from the age of 4; or by a close adult, usually present at the child's side during treatment.
Locations (5)
CHU Angers
Angers, France, France
CHU Caen FEH
Caen, France, France
Rennes University Hospital
Rennes, France, France
Institut de Cancérologie de l'Ouest René Gauducheau
Saint-Herblain, France, France
CHU Tours Hôpital Clocheville
Tours, France, France