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NCT06869304

The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases

Sponsor: Ankara City Hospital Bilkent

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period. Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.

Official title: Examining the Effect of Steep Trendelenburg Position on Neurocognitive Functions With MoCA Test in Robotic-assisted Radical Prostatectomy Surgeries.

Key Details

Gender

MALE

Age Range

65 Years - 100 Years

Study Type

OBSERVATIONAL

Enrollment

56

Start Date

2025-03-15

Completion Date

2025-10-30

Last Updated

2025-03-11

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Montreal Cognitive Assessment

Preoperative and postoperative MoCA test scores

Locations (1)

Ankara City Hospital Bilkent

Ankara, Turkey (Türkiye)