Clinical Research Directory
Browse clinical research sites, groups, and studies.
Reducing Pneumonia with LMA in Lung Wedge Resection
Sponsor: Hai Feng
Summary
This retrospective cohort study aims to evaluate whether spontaneous breathing laryngeal mask anesthesia (LMA-SBA) reduces the incidence of postoperative pneumonia compared to single-lung isolation mechanical ventilation in patients undergoing thoracoscopic wedge resection. Using propensity score overlap weighting, we will adjust for multiple confounders, including age, COPD, surgical duration, and preoperative laboratory values. Secondary outcomes include postoperative recovery time, fever severity, white blood cell count, neutrophil percentage, length of hospital stay, and ICU admission rate. The study has been approved by the Ethics Committee of the First Affiliated Hospital of Shandong First Medical University (Approval No. YXLL-KY-2025(037)).
Official title: Reducing Postoperative Pneumonia Risk with Spontaneous Breathing Laryngeal Mask Anesthesia in Thoracoscopic Wedge Resection: a Propensity Score Overlap-Weighted Multifactorial Retrospective Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
700
Start Date
2025-03-15
Completion Date
2025-04-30
Last Updated
2025-03-13
Healthy Volunteers
No
Locations (1)
Shandong First Medical University, First Affiliated Hospital (Qianfo Mountain Hospital of Shandong Province)
Jinan, Shandong, China