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Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders
Sponsor: IRCCS Eugenio Medea
Summary
The primary aim of this observational study is to investigate specific aspects of social cognition in dystrophinopathies. Body awareness, interpersonal distance and emotional processing will be measured in a sample of patients affected by Becker (BMD) and Duchenne (DMD) muscular dystrophy, compared with a sample of patients affected by osteogenesis imperfecta (OI), and both compared with a control sample with typical development. The secondary aim is to study cortical activity at rest, by means of electroencephalography (EEG), to explore frequencies and time course of EEG responses. Moreover, the relationship between EEG activity and neuropsychological, dispositional and subjective measures will be explored through correlational analyses.
Official title: Social Cognition in Dystrophinopathies and Neurodevelopmental Disorders. Behavioural and Psychophisiological Measures
Key Details
Gender
MALE
Age Range
4 Years - Any
Study Type
OBSERVATIONAL
Enrollment
45
Start Date
2025-09
Completion Date
2027-12
Last Updated
2025-03-13
Healthy Volunteers
Yes
Interventions
Electroencephalography (EEG)
Recording of resting state EEG will be collected
Social Cognition Tasks
Comfort-Distance Task: it will be used to measure the interpersonal comfort distance, the task will be implemented in immersive virtual reality environment Interoception will be measured through an auditory match task based on participants heart-beat A measure emotion processing will be collected through the emotion priming visual task, participants will be asked to detect trial by trial the target emotion which could be preceded by a congruent or incongruent visual priming