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Latent Tuberculosis in Type 2 Diabetes
Sponsor: Taichung Veterans General Hospital
Summary
The patients with poorly controlled DM underwent LTBI screening by using QuantiFERON (QFT). QFT-positivity predictors were evaluated. The patients with LTBI received tuberculosis preventive therapy, 9 months of daily isoniazid (9H) or 3 months of weekly rifapentine plus isoniazid (3HP), administered by pulmonologists. The completion rates and inflammatory markers were also investigated.
Official title: Directly Observed Preventive Therapy (DOPT) for Latent Tuberculosis Infection Patients With Poorly Controlled Diabetes Mellitus
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
552
Start Date
2018-04-18
Completion Date
2025-04-18
Last Updated
2025-03-13
Healthy Volunteers
No
Conditions
Interventions
Rifapentine and Isoniazid for 3 months
tuberculosis preventive therapy (TPT) with 3 months of weekly rifapentine plus isoniazid (3HP)
Isoniazid (INH) daily for 9 months
tuberculosis preventive therapy (TPT) with 9 months of daily isoniazid (9H)
Locations (1)
Taichung Veterans General Hospital
Taichung, Taiwan