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NOT YET RECRUITING
NCT06875206
NA

Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke

Sponsor: Duke University

View on ClinicalTrials.gov

Summary

This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS). The treatment uses ultrasound to stimulate vision specific parts of the brain. Before this therapy, the participants will get structural brain imaging. Functional brain imaging will be performed before and after the study's completion to measure brain activity response to therapy. The purpose of this research study is to evaluate patients who have had a stroke between 6 and 24 months ago with a visual field impairment. The duration of active participation in the study is 1.5 months.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

28

Start Date

2026-03-01

Completion Date

2027-04

Last Updated

2026-02-20

Healthy Volunteers

No

Interventions

DEVICE

Low-intensity focused ultrasound

Low-intensity focused Ultrasound (LIFU) is a noninvasive brain stimulation technique that uses low-intensity ultrasound to stimulate specific parts of the brain.

DEVICE

Immersive virtual reality

IVR is a noninvasive, computer-based audiovisual therapy designed to enhance visual function. Using a VR headset, the system delivers targeted visual stimulation through an interactive game that the participant engages with during each session.

DEVICE

Inactive Low-intensity focused ultrasound

High acoustic impedance disk placed between LIFU and scalp that mimics the audible sensation of a slight buzzing but attenuates more than 95% of the energy into the brain.

Locations (1)

Duke University Health System

Durham, North Carolina, United States