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ACTIVE NOT RECRUITING
NCT06878989
NA

Adaptation of Human Brown Adipose Tissue to Calorie Restriction

Sponsor: Universidad de Granada

View on ClinicalTrials.gov

Summary

The BATON study investigates how human brown adipose tissue (BAT) adapts to a controlled caloric restriction diet in young adults with obesity. A weight maintenance diet group will be compared to a group following a diet designed to induce an 8-10% weight loss over a 12-16 week period. Outcome assessments will include advanced technologies such as PET-CT and molecular analyses of BAT. The overarching goal is to gain a deeper understanding of the role of human BAT on the regulation of body weight.

Official title: Adaptation of Human Brown Adipose Tissue to Calorie Restriction (BATON)

Key Details

Gender

All

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2025-01-25

Completion Date

2026-12

Last Updated

2026-05-12

Healthy Volunteers

No

Interventions

BEHAVIORAL

Caloric restriction diet

Dietary intervention consisting on a meal plan designed to induce an 8-10% weight loss over a 12-16 week period.

BEHAVIORAL

Weight maintenance diet

Dietary intervention consisting on a meal plan designed to maintain a stable body weight for up to 16 weeks.

Locations (1)

Department of Physiology, Faculty of Medicine, University of Granada.

Granada, Granada, Spain