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Comparing IVF/ICSI Cycle Outcomes of Post Ovulation Ovarian Stimulation Protocol With Elonva Without GnRH Antagonist to Follicular Phase Day 2 Stimulation Fixed Day 5 Antagonist Protocol
Sponsor: ART Fertility Clinics LLC
Summary
There are several approaches to the timing of antagonist administration in IVF/ICSI cycles. The primary goal is indeed to prevent premature ovulation, which could jeopardize the success of the cycle There is an emerging concept that suggests that the progesterone produced by the corpus luteum (formed after ovulation) might be sufficient to prevent further ovulation, obviating the need for antagonist or exogenous progesterone administration. This hypothesis relies on the natural regulatory mechanisms of the menstrual cycle to maintain a progesterone-dominated environment post-ovulation. We hypothesized that this approach would minimize treatment costs /burden without having an impact on the outcome.
Official title: To Compare IVF/ICSI Cycle Outcomes of Post Ovulation Ovarian Stimulation Protocol With Elonva Without GnRH Antagonist to Follicular Phase Fixed Day 5 Antagonist Protocol
Key Details
Gender
FEMALE
Age Range
18 Years - 38 Years
Study Type
OBSERVATIONAL
Enrollment
252
Start Date
2025-12-30
Completion Date
2026-12-30
Last Updated
2025-10-02
Healthy Volunteers
Yes
Conditions
Interventions
Ovarian stimulation with menstruation or after ovulation
Ovarian stimulation with menstruation or after ovulation
Locations (2)
ART Fertility Clinics LLC
Abu Dhabi, United Arab Emirates
ART Fertility Clinics LLC - Dubai
Dubai, United Arab Emirates