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NOT YET RECRUITING
NCT06879002

Comparing IVF/ICSI Cycle Outcomes of Post Ovulation Ovarian Stimulation Protocol With Elonva Without GnRH Antagonist to Follicular Phase Day 2 Stimulation Fixed Day 5 Antagonist Protocol

Sponsor: ART Fertility Clinics LLC

View on ClinicalTrials.gov

Summary

There are several approaches to the timing of antagonist administration in IVF/ICSI cycles. The primary goal is indeed to prevent premature ovulation, which could jeopardize the success of the cycle There is an emerging concept that suggests that the progesterone produced by the corpus luteum (formed after ovulation) might be sufficient to prevent further ovulation, obviating the need for antagonist or exogenous progesterone administration. This hypothesis relies on the natural regulatory mechanisms of the menstrual cycle to maintain a progesterone-dominated environment post-ovulation. We hypothesized that this approach would minimize treatment costs /burden without having an impact on the outcome.

Official title: To Compare IVF/ICSI Cycle Outcomes of Post Ovulation Ovarian Stimulation Protocol With Elonva Without GnRH Antagonist to Follicular Phase Fixed Day 5 Antagonist Protocol

Key Details

Gender

FEMALE

Age Range

18 Years - 38 Years

Study Type

OBSERVATIONAL

Enrollment

252

Start Date

2025-12-30

Completion Date

2026-12-30

Last Updated

2025-10-02

Healthy Volunteers

Yes

Interventions

OTHER

Ovarian stimulation with menstruation or after ovulation

Ovarian stimulation with menstruation or after ovulation

Locations (2)

ART Fertility Clinics LLC

Abu Dhabi, United Arab Emirates

ART Fertility Clinics LLC - Dubai

Dubai, United Arab Emirates