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Mitochondrial Function and Metabolomic Profile in Alzheimer's Disease and Related Dementias
Sponsor: Centre Hospitalier Universitaire de Nice
Summary
This project aims to study on one hand the early mitochondrial alterations, common or specific, occurring in peripheral cells of patients with Alzheimer's disease or related dementia and, on the other hand, identify the metabolomic biomarkers that may be at the origin of mitochondrial disturbances associated with the disease. This will be the first study combining functional analyses of mitochondria and exploratory metabolomic assessments in the same cohort at early stages of the disease.
Official title: Early Alterations of Peripheral Mitochondrial Function and Metabolomic Profile in Patients With Alzheimer's Disease and Related Dementias
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
170
Start Date
2025-07-01
Completion Date
2029-04-01
Last Updated
2025-07-03
Healthy Volunteers
No
Conditions
Interventions
MMSE and blood draw
Each patient will be evaluated by Mini-Mental State Examination (MMSE) and will have a blood draw
Locations (1)
CHU de Nice
Nice, PACA, France