Clinical Research Directory
Browse clinical research sites, groups, and studies.
Nervus Vagus Stimulation and Cerebral Palsy
Sponsor: Istanbul Medipol University Hospital
Summary
When the literature is reviewed, it is difficult to find direct research on the effects of auricular vagus nerve stimulation (aVNS) on the autonomic nervous system and spasticity in children with spastic cerebral palsy. However, there is a substantial body of literature on the potential of vagus nerve stimulation (VNS) to modulate autonomic functions. The aim of this study is to investigate the potential effects of vagus nerve stimulation, which is known to influence the autonomic nervous system, in individuals with spastic cerebral palsy and to explore its contributions to spasticity.
Official title: The Acute Effects of Vagus Nerve Stimulation on the Autonomic Nervous System and Spasticity in Children with Spastic Cerebral Palsy
Key Details
Gender
All
Age Range
2 Years - 15 Years
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2025-03-01
Completion Date
2025-05-01
Last Updated
2025-03-18
Healthy Volunteers
No
Conditions
Interventions
nervus vagus stimulation
Vagus stimulation was applied bilaterally through the ear in a transcutaneous manner. transcutaneous auricular VNS (taVNS) was performed using the Vagustim device. The stimulation was applied for 20 minutes with a pulse width of 300 microseconds, a frequency of 10 Hz, and in a biphasic manner. The electrodes were placed on the concha and tragus parts of the ear, and the current was increased until the participant could feel it.
Locations (1)
Mudanya University
Bursa, Bursa, Turkey (Türkiye)