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RECRUITING
NCT06882967

Active Thoracic Compromised Distal LANding in TEvar

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

View on ClinicalTrials.gov

Summary

Thoracic endovascular aortic repair (TEVAR) has become the mainstay of aortic intervention for descending thoracic aortic pathology. Its durability hinges on achieving adequate seal in the endograft landing zones (LZs), with the distal LZ largely understudied. Only recently are suboptimal distal LZs receiving attention for their role in major complications including stent graft migration, type 1B endoleaks, and distal stent graft-induced new entry tears, all of which can contribute to further aortic degeneration. The thoracic distal LZ. When a short distal LZ was reported, the distal endoleak rate ranged from 3.5% to 33%. This led to reintervention in 19%, along with coverage of the celiac trunk in more than half of short LZ cases. The objective of this study was to evaluate the outcomes of TEVAR patients with compromised distal landing zone (CDLZs) treated with distal active fixation stent-grafts (DAFs), distal scallop stent-grafts, distal Aptus Heli-FX EndoAnchors, and standard stent-grafts.

Official title: Thoracic Endovascular Aortic Repair in Compromised Distal Landing Zones

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2022-11-01

Completion Date

2027-11-01

Last Updated

2025-03-19

Healthy Volunteers

No

Interventions

DEVICE

Thoracic Endovascular Aortic Repair

Placement of a covered stent (a metal mesh tube with a layer of fabric) into the weakened area of the artery.

Locations (1)

Fondazione Policlinico Universitario A. Gemelli IRCCS

Roma, RM, Italy