Clinical Research Directory

Inclusion Criteria: * Patients after hospitalization for acute heart failure (AHF) * Symptoms (shortness of breath, oedema, decreased exercise tolerance, increase in abdominal circumference) * Clinical signs (jugular vein distention, hepatojugular reflux, third heart sound, wet lung crackles, pitting oedema) or signs of congestion on CT, X-ray or ultrasound * NT-proBNP \>450 pg/mL \<55 years old, \>900 pg/mL 55-75 years old, \>1800 pg/mL \>75 years old * Increase in oral diuretic therapy or need for IV diuretics Exclusion Criteria: * pregnancy or lactation * under 18 years of age, * current AHF due to a transient cause (Takotsubo syndrome, neurogenic myocardial stunning, septic cardiomyopathy, cardiac tamponade, pulmonary embolism with acute cor pulmonale, thyrotoxicosis, bradycardia \<40/min) * planned surgical treatment of the HF cause, CRT implantation or valvular repair ≤ 30 days ago, STEMI or coronary angiography with PCI or CABG ≤ 30 days ago, untreated AV block III. and II. degree type 2, planned or previous heart transplantation, myocarditis ≤ 6 months ago, complex congenital heart disease, cardiac amyloidosis, hypertrophic and restrictive cardiomyopathy, constrictive pericarditis * BMI over 40 kg/m2, cognitive deficit with MMSE \<18 points, life expectancy \< 12 months, progressive oncological disease, chronic liver failure Child-Pugh C, chronic kidney disease with eGFR \<0.25 ml/s * current participation in another study or relative of investigators