Clinical Research Directory

Inclusion Criteria: * o Patients with asymptomatic deep carious molars. * Patients with clinically and radiographically confirmed deep carious lesions that do not exhibit spontaneous pain. * Permanent molars only. * Teeth with intact or minimally restored occlusal surfaces (i.e., no extensive restorations or fractures). * No history of previous endodontic treatment or direct pulp capping on the study tooth. * No signs of periapical pathology based on radiographic evaluation. * Patients willing to participate and follow up for 12 months. * Patients who agree to return for scheduled follow-ups at 3, 6, and 12 months. Exclusion Criteria: * o Patients with systemic conditions affecting bone or tissue healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppressed conditions). * Pregnant or lactating women (if applicable to your study). * Teeth with pulp exposure or necrotic pulp. * Presence of symptomatic irreversible pulpitis (e.g., spontaneous pain, lingering pain). * Periapical pathology or internal/external resorption detected radiographically. * Severely broken down or non-restorable teeth. * Calcified root canals or excessive sclerosis that could affect pulp testing reliability. * Any pre-existing root canal treatment on the selected tooth. * Patients who have undergone recent fluoride treatment, pulpotomy, or other pulp therapies in the past 6 months. * Patients using medications affecting bone and tissue regeneration (e.g., bisphosphonates, corticosteroids). * Patients unwilling or unable to commit to the 12-month follow-up schedule. * Patients with poor oral hygiene or high caries risk that could compromise treatment outcomes.