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Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS
Sponsor: Attikon Hospital
Summary
The aim of the present study is to investigate a) the presence of subclinical markers of vascular, myocardial and endothelial function in women with PCOS b) the acute alterations in these markers during the oral glucose tolerance test (OGTT) c) the impact of potential treatment interventions in these markers.
Official title: The Effect of Different Treatment Options on Markers of Vascular, Myocardial and Endothelial Function in Women With Polycystic Ovary Syndrome and the Association With Metabolic and Hormonal Abnormalities of the Syndrome
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2024-02-01
Completion Date
2026-02-01
Last Updated
2025-11-19
Healthy Volunteers
No
Interventions
GLP-1 receptor agonist
30 women will receive lifestyle modification and GLP-1 receptor agonists
Oral contraceptive
30 women will receive lifestyle modification and oral contraceptive
Metformin
30 women will receive lifestyle modification and metformin
Lifestyle modification
30 women will receive only lifestyle modification
Locations (1)
Attikon University General Hospital
Chaïdári, Greece