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Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)
Sponsor: University Hospital, Strasbourg, France
Summary
While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which can occur in up to 30% of patients. Anticoagulation is the primary preventive measure recommended in clinical practice to reduce the risk of this complication, typically involving heparin injection during the procedure in most centers. However, data on the effect of the timing of heparin injection are limited. The investigators hypothesize that injection of heparin before sheath insertion may reduce the rate of radial artery occlusion compared with injection after sheath insertion.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
550
Start Date
2025-06-05
Completion Date
2026-01
Last Updated
2025-09-05
Healthy Volunteers
No
Conditions
Interventions
Administration of heparin after sheath insertion
Administration of heparin after sheath insertion
Administration of heparin prior to sheath insertion
Administration of heparin prior to sheath insertion
Locations (1)
Hôpitaux Universitaires de Strasbourg
Strasbourg, Bas-Rhin, France