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Stellate Ganglion Blockade for Refractory Chronic Migraine
Sponsor: Ankara City Hospital Bilkent
Summary
Stellate Ganglion Block (SGB) is an interventional anesthetic technique used to treat pain conditions affecting the head, face, neck, and upper extremities by temporarily blocking sympathetic nerve output. Ultrasound guidance improves anatomical visualization and facilitates accurate needle placement. Emerging evidence suggests that repeated ultrasound-guided SGB may be associated with reductions in headache intensity and frequency in patients with migraine and with improvement in migraine-related disability. However, limited data exist regarding its use in highly treatment-resistant chronic migraine, particularly in patients who have not responded adequately to preventive pharmacological therapies and prior interventional treatments. The primary objective of this study is to evaluate 6-month clinical outcomes following ultrasound-guided SGB in patients with treatment-resistant chronic migraine. Secondary objectives include assessing changes in pain intensity, migraine-related disability, analgesic use, patient-reported global improvement, and treatment tolerability.
Official title: Ultrasound-Guided Stellate Ganglion Block for Refractory Chronic Migraine: A Prospective Evaluation
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2024-03-06
Completion Date
2025-12-30
Last Updated
2026-09-09
Healthy Volunteers
No
Interventions
Procedure/Surgery: Ultrasound-Guided Stellate Ganglion Block
Ultrasound-guided SGB was performed under sterile conditions with intravenous access and continuous monitoring. With the patient in the supine position, a linear ultrasound probe was placed transversely at the C6 level to identify the longus colli muscle, prevertebral fascia, carotid artery, internal jugular vein, thyroid gland, and adjacent vascular structures. A 22-gauge, 90-mm needle was advanced using an in-plane lateral-to-medial approach toward the prevertebral fascia anterior to the longus colli muscle. After negative aspiration and confirmation of needle position, 5 mL of 1% lidocaine was administered. For bilateral headache distribution, bilateral blocks were performed sequentially with a minimum 60-minute interval between sides.
Locations (1)
Health Sciences University, Ankara Bilkent City Hospital
Ankara, Cankaya, Turkey (Türkiye)