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Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions
Sponsor: Icahn School of Medicine at Mount Sinai
Summary
This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (pleural biopsy) obtain an adequate biopsy, achieve a diagnosis, and begin cancer-directed therapy faster.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
98
Start Date
2025-03-24
Completion Date
2026-09-17
Last Updated
2026-02-04
Healthy Volunteers
No
Conditions
Interventions
Pleuroscopy first
Pleuroscopies are performed under moderate sedation with local anesthesia. Through a 1-cm incision a camera is introduced into the pleural space and the space is inspected after draining all fluid. Targeted biopsies under direct visualization are obtained using forceps. The aspirated fluid and biopsies obtained are sent to the cytology and pathology laboratories for analysis.
Thoracentesis first
Thoracenteses are performed under local anesthesia with the insertion of a 5-8Fr catheter into the pleural space. The aspirated fluid obtained is sent to the cytology laboratory for analysis.
Locations (2)
Mount Sinai West
New York, New York, United States
Mount Sinai Hospital
New York, New York, United States