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Multicenter Prospective Observational Study on Diaphragmatic Function Assessment by Ultrasound in Patients with Acute Respiratory Failure Receiving Non-invasive Mechanical Ventilation or High Flow Nasal Canula
Sponsor: Foro Internacional en Cuidado Crítico
Summary
The primary goal of this study is to assess diaphragm function in patients with acute respiratory failure before and during the use of high-flow oxygen and/or non-invasive breathing support. The key question it seeks to answer is: 1\. How do ultrasound measurements of diaphragmatic function vary with different levels of breathing support in patients with acute respiratory failure? Participants with acute respiratory failure will undergo diaphragmatic ultrasound evaluation as part of their standard medical care at various levels of respiratory support.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-06-02
Completion Date
2026-06-01
Last Updated
2025-03-25
Healthy Volunteers
No
Conditions
Interventions
Diaphragmatic ultrasound
Sample: Given the observational nature of the study, a convenience sample will be obtained from all patients admitted to the emergency services and/or ICU with respiratory failure over the course of 1 year. Inclusion Criteria: * Age ≥ 18 years * Hypoxemic respiratory failure (SpO2 \< 88% - PaO2 \< 60 mmHg) or hypercapnic (PaCO2 \> 40) * Need for NIMV and/or HFNC. Exclusion Criteria: * Neuromuscular disease * Pregnancy * Tracheostomy * Rib fractures * Cervical injuries * Diaphragmatic paralysis * Diaphragmatic malformations * Hemodynamic instability * Morbid obesity (BMI \> 35) * Use of sedation and neuromuscular relaxants * Pneumothorax or pneumomediastinum * Poor acoustic window * Critically ill patients with a prognosis of less than 24 hours of life * Patients receiving palliative interventions.