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RECRUITING
NCT06894992
NA

Tegoprazan And Lansoprazole Effectiveness in Bleeding Peptic Ulcer Treatment

Sponsor: Mario Steffanus

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to compare the effects of tegoprazan vs lansoprazole in healing bleeding peptic ulcers. It will also teach about the safety of both modalities. The main questions it aims to answer are: How does the effectiveness of Tegoprazan compare with Lansoprazole in two weeks of healing rate bleeding peptic ulcer patients in the Indonesian population? Researchers will compare the drug tegoprazan to lansoprazole with a double-blind randomized control to see their effect on healing bleeding peptic ulcers. Participants will: Take drug tegoprazan 50 mg OD or lansoprazole 30 mg OD every day for 2 weeks Endoscopic examination at the beginning before treatment and after completion of treatment within 2 weeks Record of their adverse effect occurrence

Official title: A Comparison of The Effectiveness of Tegoprazan and Lansoprazole in Achieving Cure Rates in Patients With Bleeding Peptic Ulcers: A Double-Blind Randomized Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

162

Start Date

2025-05-01

Completion Date

2025-12-31

Last Updated

2025-05-29

Healthy Volunteers

No

Interventions

DRUG

Tegoprazan

Tegoprazan 50 mg tab PO OD in 2 weeks

DRUG

Lansoprazole

Lansoprazole 30 mg tab PO OD in 2 weeks

Locations (2)

Cipto Mangunkusumo National General Hospital

Jakarta, DKI Jakarta, Indonesia

Atma Jaya Hospital

Jakarta, DKI Jakarta, Indonesia