Clinical Research Directory

Inclusion Criteria: * Age \>18 years and \<75 years * Unilateral supratentorial ischemic stroke that occurred at least 7 days but not more 30 days before enrollment. * Modified Rankin Scale between 0 and 1 before stroke * Contralesional UL motor impairment defined by NIHSS item 5 score ≥ 1 to ≤ 3. * Ability to provide written informed consent. * Hemodynamically stable patients. * Patients residing in the metropolitan area of Bucaramanga. Exclusion Criteria: * Significant cognitive or language impairment that would interfere with study participation or informed consent. This criterion will be defined by NIHSS item 1a-c score \> 2, item 9 score \> 1, item 11 score = 2. * Medical conditions that could interfere with study participation, for example ear infections or skin wounds. * Bradycardia (\< 50 bpm) or hypotension (\< 90/60 mmHg) * Significant pre-existing disability * History of stroke * History of cardiac arrhythmia * History of severe head trauma, brain surgery, deep brain stimulation, or brain injuries of other etiologies. * Pregnant or planning on becoming pregnant or breastfeeding during the study period. * Medical or mental instability (diagnosis of personality disorder, psychosis, or substance abuse) that would prevent subject from meeting protocol timeline. * Subjects who are currently in another clinical trial or plan to do so during the study period. * Patient receiving any therapy at study entry that would interfere with VNS (e.g., drugs that interfere with neurotransmitter mechanisms: anticholinergics, adrenergic blockers, etc.). * Prior injury to vagus nerve. * Any other implanted device such as a pacemaker or other neurostimulator; any other investigational device or drug.