TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

RECRUITING

NCT06896227

NA

Sponsor: Heinrich-Heine University, Duesseldorf

Summary

The aim of this clinical study is to learn more about the effects of TAVR-prosthesis positioning on hemodynamics and the coronary arteries. The main questions it aims to answer are: 1. Does the cardiac magnetic resonance imaging and the echocardiography imaging provide an equivalent alternative to the computer tomography which is the state of the art in evaluating commissural alignment? 2. What effect does the position of the valve on the annular level have, especially its symmetrical and commissural position, on valvular and aortic blood flow characteristics? 3. What is the influence of symmetrical position and the presence of a commissural alignment on the coronary flow after transcatheter aortic valve replacement?

Official title: Transcatheter Aortic Valve Implantation (TAVR): The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2024-10-22

Completion Date

2025-12-31

Last Updated

2025-03-26

Healthy Volunteers

No

Conditions

Transcatheter Aortic Valve Replacement Transcatheter Aortic Valve Implantation Commissural Alignment Commissural Misalignment Symmetry Prothesis Positioning Prosthesis Durability Aortic Valve Stenosis Aortic Valve Disease

Interventions

DIAGNOSTIC_TEST

transthoracic echocardiography

Each study patient will undergo transthoracic echocardiography, transesophageal echocardiography, and cardiac magnetic resonance imaging following transcatheter aortic valve replacement.

Locations (1)

Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf

Düsseldorf, Germany

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