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RECRUITING
NCT06898723
PHASE4

The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis

Sponsor: First Affiliated Hospital of Wannan Medical College

View on ClinicalTrials.gov

Summary

This study focuses on improving heart function in patients with life-threatening blood infections (septic shock). When the body fights severe infections, the heart sometimes struggles to pump blood effectively, which can lead to dangerous complications. Current treatments like intravenous fluids and blood pressure medications have limitations in protecting heart function. This multicenter clinical trial aims to evaluate whether adding Shenfu Injection - a traditional Chinese medicine preparation widely used to enhance cardiac function in cardiovascular diseases - to standard therapies can: 1. Prevent myocardial dysfunction during septic shock 2. Accelerate cardiac recovery if complications occur 3. Improve overall survival and clinical outcomes The randomized controlled design will compare therapeutic effects between two groups: one receiving standard septic shock treatment alone, and the other receiving standard treatment combined with Shenfu Injection.

Official title: The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis: a Multicenter, Randomized Controlled Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

440

Start Date

2024-10-01

Completion Date

2026-09-30

Last Updated

2025-03-27

Healthy Volunteers

No

Interventions

DRUG

Shenfu Injection

The treatment will utilize Ginseng and Aconite Injection, which primarily consists of Red Ginseng and Aconite

Locations (1)

The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)

Wuhu, Anhui, China