Clinical Research Directory

Inclusion Criteria: * Age ≥ 18 years * Patients with symptomatic coronary artery disease (including those with acute coronary syndromes or Chronic Coronary Syndromes) with either symptoms and/or ischaemia. * The patient must be able to understand and provide informed consent and comply with all study procedures. Coronary angiographic inclusion criteria: * ≥70% target lesion stenosis in LAD, LCX or RCA (or branches) which after successful pre-dilatation\* has a residual stenosis ≤ 30% and no dissection of Type C or greater than (NHLBI guidelines) \*pre-dilation permitted with SC or NC balloon catheter, cutting/scoring balloon, rotational/orbital atherectomy, or laser * Target vessel reference diameter between 2.0 and 4.5 mm. Exclusion Criteria: * Left ventricular ejection fraction (LVEF) ≤ 30% * Acute ST elevation MI (STEMI) * Cardiogenic shock within 2 days prior to the index PCI. * Known contraindication or hypersensitivity to paclitaxel, and/or to any anti-thrombotic and anti-platelet class of drugs * Allergy to imaging contrast media which cannot be adequately pre-medicated. * Patient undergoing planned surgery within 3 months with the necessity to stop dual antiplatelet therapy (DAPT). * Patient is pregnant or breast feeding. * Patient has received a heart transplant. * Patient is unwilling or unable to give follow-up until study completion. * Patient is currently participating in another trial. * Life expectancy \<1 year. Angiographic exclusion criteria: * Target lesion in the left main coronary artery. * Flow limiting target vessel thrombus * Vessel dissection requiring bailout stenting.