Clinical Research Directory
Browse clinical research sites, groups, and studies.
Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department
Sponsor: Wake Forest University Health Sciences
Summary
The goal of this proposal is to improve the quality and value of care for patients with acute chest pain by investigating the potential impact of point-of-care (POC) high sensitivity cardiac troponin (hs-cTn) testing in the Emergency Department (ED) and exploring how best to integrate POC hs-cTnl into ED risk stratification workflows. The study hypothesizes that the Abbott i-STAT POC hs-cTnI assay will decrease time-to-result (TTR) and ED length of stay (LOS), while increasing ED revenue for patients with acute chest pain compared to a strategy of central laboratory hs-cTnI testing.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
600
Start Date
2025-02-07
Completion Date
2026-07
Last Updated
2026-02-02
Healthy Volunteers
No
Conditions
Interventions
Abbott i-STAT point of care (POC) device
During the study period all ED patients with chest pain will have an extra lithium heparin blood sample obtained for each troponin test ordered and collected in the ED (typically 2, but this may range from 1-3 troponin measures), which will be used for immediate hs-cTnI measurement by research personnel using an Abbott i-STAT POC device.
Locations (3)
Carolinas Medical Center
Charlotte, North Carolina, United States
High Point Medical Center
High Point, North Carolina, United States
Wake Forest School of Medicine
Winston-Salem, North Carolina, United States