Clinical Research Directory

Key Inclusion Criteria: * Male，4-8 years old at the beginning of screening (including boundary values; * DMD subjects with a clinical diagnosis of DMD referred to the Duchenne Clinical Practice Guidelines for Progressive Muscular Dystrophy (2020 edition) and whose genetic test results were confirmed to be applicable to exon skipping at No.51. * The subjects and/or his guardian voluntary participate in this trial and can comprehend and sign ICF. Key Exclusion Criteria: * Clinical signs of heart failure: left ventricular ejection fraction (LVEF) \<40%； * The average FVC percentage of the predicted value is less than 40%； * 12 lead ECG QT interval (QTc) \>0.45 seconds.