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The Diagnostic Application of PSMAPET/MR in Patients Undergoing Secondary Prostate Puncture
Sponsor: Nanjing First Hospital, Nanjing Medical University
Summary
The present study is designed to explore the value of targeted puncture guided by PSMA PET/CT or mpMRI in the diagnosis of patients with low PSA and initial negative prostate biopsy
Official title: The Diagnostic Application of PSMA PET/MR in Patients with PSA <20 Ng/ml and Initial Negative Prostate Biopsy
Key Details
Gender
MALE
Age Range
40 Years - Any
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-06-01
Completion Date
2028-06-01
Last Updated
2025-03-30
Healthy Volunteers
No
Conditions
Interventions
Prostate biopsy guided by PSMA PET/CT
The patient will undergo pelvic non-contrast CT imaging. After co-registration of the CT images with 68Ga-PSMA PET/CT data at corresponding anatomical levels, a percutaneous gluteal approach will be utilized for CT-guided prostate biopsy.
Prostate biopsy guided by mpMRI/US
The patient will undergo transrectal ultrasound (TRUS) prostate scanning. After co-registration and precise image fusion of TRUS findings with multiparametric MRI (mpMRI) data, a transperineal percutaneous approach will be employed to perform TRUS-guided prostate biopsy.
Systematic prostate biopsy
The patient will undergo systematic prostate biopsy under TRUS guidance.
Locations (1)
Nanjing First Hospital
Nanjing, Jiangsu, China