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A Study of YZJ-4729 Tartrate Injection for the Treatment of Pain After Orthopedic Surgery
Sponsor: Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
Summary
The primary objective is to evaluate the analgesic efficacy and safety of IV YZJ-4729 Tartrate Injection in patients with acute postoperative pain following Orthopedic surgery
Official title: A PhaseⅡ, Randomized, Double-Blind, Placebo- and Active- Controlled Study of YZJ-4729 Tartrate Injection for the Treatment of Moderate to Severe Pain After Orthopedic Surgery
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2025-04
Completion Date
2025-11
Last Updated
2025-03-30
Healthy Volunteers
No
Conditions
Interventions
YZJ-4729
Loading dose + demand dose
Placebo Comparator: Saline
Loading dose + demand dose
Active Comparator: Morphine
Loading dose + demand dose
Locations (21)
The Third Xiangya Hospital of Central South University
Changsha, China
Chengdu Second People's Hospital
Chengdu, China
Sichuan Provincial People's Hospital
Chengdu, China
The Third People's Hospital of Chengdu
Chengdu, China
The First Hospital of Jilin University
Ch’ang-ch’un, China
Dalian University Affiliated Zhongshan Hospital
Dalian, China
Dongguan People's Hospital
Dongguan, China
The First Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, China
The Second People's Hospital of Hefei
Hefei, China
Jinhua Central Hospital
Jinhua, China
Mianyang Central Hospital
Mianyang, China
The First Affiliated Hospital of Nanchang University
Nanchang, China
Zhongda Hospital Southeast University
Nanjing, China
Ningbo Medical Center Lihuili Hospital
Ningbo, China
The First Affiliated Hospital of Ningbo University
Ningbo, China
The Second Affiliated Hospital of Fujian Medical University
Quanzhou, China
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
Shanghai First People's Hospital
Shanghai, China
The Third Hospital of Hebei Medical University
Shijiazhuang, China
Suzhou University Affiliated Second Hospital
Suzhou, China
Henan Provincial People's Hospital
Zhengzhou, China