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Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel
Sponsor: Pakistan Institute of Medical Sciences
Summary
The goal of this clinical trial is to learn the effect of Nano-fortified Bleaching on whitening and sensitivity of teeth.The main questions it aims to answer are: Does Nano-fortified Bleaching gel is more effective in enhancing the whitening in comparison to conventional bleaching gel ? Does Nano-fortified Bleaching gel is more effective in declining the sensitivity in comparison to conventional bleaching gel ? Participants will be divided into 2 groups i.e Group A where Nano-fortified Bleaching agent will be employed and Group B where Conventional Bleaching agent without nanoparticles will be used. Two application of bleaching for 16 minutes twice with total of thirty two minutes in a single session will be carried out . Tooth sensitivity will be measured by VAS Scale having "No Pain" at one-end and "Worst Pain" at opposite-end .Color change will be measured with spectrophotometer.
Official title: Clinical Efficacy of Novel Titanium Oxide Nanoparticle Enriched Bleaching Gel on Tooth Whitening and Hypersensitivity: A Randamized Clinical Trial.
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-06-13
Completion Date
2024-12-27
Last Updated
2026-08-31
Healthy Volunteers
Yes
Conditions
Interventions
Nano-reinforced Novel Hydrogen peroxide gel
Group A (Novel Nano-enriched Hydrogen peroxide bleaching gel with Silky Corn hair fiber derived- titania nanoparticles)
Conventional Hydrogen peroxide gel without nanoparicles
Drug: Hydrogen peroxide without nanoparicles Group B ( Conventional Hydrogen peroxide gel without nanoparticles)
Locations (1)
School of Dentistry, Pakistan Institute of Medical Sciences
Islamabad, Punjab Province, Pakistan