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RECRUITING
NCT06904287
PHASE3

Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

Sponsor: Wake Forest University Health Sciences

View on ClinicalTrials.gov

Summary

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

Official title: Evaluating the Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines in the Emergency Department

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2025-12-16

Completion Date

2027-06

Last Updated

2026-01-22

Healthy Volunteers

No

Conditions

Interventions

DRUG

Magnesium

Prochlorperazine 10 mg administered as an intravenous push over 2 minutes followed by magnesium 2 g administered as an intravenous bolus over a period of 20 minutes

DRUG

Placebo

Prochlorperazine 10 mg administered as an intravenous push over 2 minutes followed by placebo (normal saline)

Locations (1)

Advocate Christ Medical Center Emergency Department

Oak Lawn, Illinois, United States