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Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines
Sponsor: Wake Forest University Health Sciences
Summary
The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.
Official title: Evaluating the Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines in the Emergency Department
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-12-16
Completion Date
2027-06
Last Updated
2026-01-22
Healthy Volunteers
No
Conditions
Interventions
Magnesium
Prochlorperazine 10 mg administered as an intravenous push over 2 minutes followed by magnesium 2 g administered as an intravenous bolus over a period of 20 minutes
Placebo
Prochlorperazine 10 mg administered as an intravenous push over 2 minutes followed by placebo (normal saline)
Locations (1)
Advocate Christ Medical Center Emergency Department
Oak Lawn, Illinois, United States