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Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants
Sponsor: BeiGene
Summary
The purpose of this study is to investigate the effect of coadministration of phenytoin or itraconazole on the pharmacokinetics of BGB-16673 in healthy participants.
Official title: A Phase 1, Open-label, Fixed-sequence, Crossover Study to Investigate the Effect of Coadministration of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-16673 in Healthy Participants
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
37
Start Date
2025-04-03
Completion Date
2025-10-13
Last Updated
2026-08-24
Healthy Volunteers
Yes
Conditions
Interventions
BGB-16673
Administered orally
Itraconazole
Administered orally
Phenytoin
Administered orally
Locations (1)
Fortrea Clinical Research Unit Inc
Madison, Wisconsin, United States