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COMPLETED
NCT06906809
PHASE1

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

Sponsor: BeiGene

View on ClinicalTrials.gov

Summary

The purpose of this study is to investigate the effect of coadministration of phenytoin or itraconazole on the pharmacokinetics of BGB-16673 in healthy participants.

Official title: A Phase 1, Open-label, Fixed-sequence, Crossover Study to Investigate the Effect of Coadministration of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-16673 in Healthy Participants

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

37

Start Date

2025-04-03

Completion Date

2025-10-13

Last Updated

2026-08-24

Healthy Volunteers

Yes

Interventions

DRUG

BGB-16673

Administered orally

DRUG

Itraconazole

Administered orally

DRUG

Phenytoin

Administered orally

Locations (1)

Fortrea Clinical Research Unit Inc

Madison, Wisconsin, United States